frantic
at one's wits' end, at the end of one's tether, berserk, beside oneself, desperate, distracted, distraught, fraught (informal) frenetic, frenzied, furious, hectic, mad, overwrought, raging, raving, uptight (informal) wild
Antonyms
calm, collected, composed, cool, laid-back, poised, self-possessed, together (slang) unfazed (informal) unruffled