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de-seed
deacon
deactivate
dead

de- 
1  prefix De- is added to a verb in order to change the meaning of the verb to its opposite. 
...becoming desensitized to the harmful consequences of violence., ...how to decontaminate industrial waste sites.  
2  prefix De- is added to a noun in order to make it a verb referring to the removal of the thing described by the noun. 
I've defrosted the freezer..., The fires are likely to permanently deforest the land.